This paper explores the potential of Actor Network Theory (ANT) in understanding how the process of interaction and translation between human and non-human actors contribute to the development, adoption and diffusion of science-based innovations linked to the transition to organic farming. The study relies on two case studies, the French Camargue case covering a range of technical and social innovations, and the case from Bulgaria focusing on the development of a technical and product innovation, i.e. a veterinary product for organic beekeeping.