This paper begins with a brief review of research on nutrition-sensitive value chains in developing countries. It then presents the Value Chains and Nutrition framework for intervention design that explores food supply and demand conditions across a portfolio of local value chains that are relevant for improving nutrition outcomes. The authors explore the framework in a case study on rural Malawi. Available evidence highlights the dominance of maize in diets, but also the willingness of rural households to consume other nutritious foods (e.g.