Agricultural biotechnology and, specifically, the development of genetically modified (GM) crops have been controversial for several reasons, including concerns that the technology poses potential negative environmental or health effects, that the technology would lead to the (further) corporatization of agriculture, and that it is simply unethical to manipulate life in the laboratory. GM crops have been part of the agricultural landscape for more than 15 years and have now been adopted on more than 170 million hectares (ha) in both developed countries (48%) and developing countries (52%).

The purpose of this report is to provide some of the groundwork in answering the question of how the CGIAR system and other public agricultural research organisations should adapt and respond to an era of transformation framed by the SDGs. It does this by exploring the way in which this transformation agenda reframes agricultural research and innovation.

Drawn from numerous sources, including papers in this journal, this concluding paper synthesizes evidence on the relationship between agricultural research for development and poverty reduction, with particular emphasis on agri-food systems perspectives in shaping programs aimed at rural prosperity. Following the introduction in section 1, we revisit the ex ante set of 18 pathways in section 2 (which were laid out in our introductory paper for this SI), posing some critical questions: Can a manageable set of impact pathways be identified? How are they inter-related?

The topics addressed in this book are of vital importance to the survival of humankind. Agricultural biodiversity, encompassing genetic diversity as well as human knowledge, is the base upon which agricultural production has been built, and protecting this resource is critical to ensuring the capacity of current and future generations to adapt to unforeseen challenges.