This research is dedicated to illuminating the relationship between knowledge and innovation within agrifood supply chains (ASCs) – although insightful and informative – is marked by conceptual and methodological issues that restrict our ability to understand the ways knowledge affects innovation and vice versa. In this work, adopting a systems approach to ASCs and synthesizing literature from different fields of study, we discuss the metaphors that guide research in this area, and we propose an alternative conceptualization of ASCs